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      產(chǎn)品中心

      CA IX/Carbonic Anhydrase IX Mouse mAb
      EM1076
      規(guī)格: 價(jià)格:
      50μL ¥1280.00
      100μL ¥1980.00

      Overview

      Product name: CA IX/Carbonic Anhydrase IX Mouse mAb
      Reactivity: Human
      Alternative Names: CA9, CAIX, Carbonate dehydratase IX, Carbonic anhydrase 9, carbonic anhydrase IX, G250, Membrane antigen MN, MN, P54/58N, pMW1, RCC associated antigen G250
      Source: Mouse
      Dilutions: WB 1:3,000 IP 1:200? IHC 1:100-200
      Immunogen: Synthetic Peptide
      Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
      Clonality: Monoclonal
      Isotype: IgG1
      Concentration: 1mg/mL
      Observed Band: 35-38kDa
      GeneID: 768
      Human Swiss-Prot No: Q16790
      Cellular localization: Nucleus. Nucleus, nucleolus. Cell membrane. Cell projection, microvillus membrane.
      Background: The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons (or vice versa), a reversible reaction that occurs rather slowly in the absence of a catalyst. CAIX is considered to be one of the best cellular biomarkers of hypoxia. Furthermore, recent studies examining the association between CAIX levels and various clinicopathological outcomes suggest that CAIX expression may also be a valuable prognostic indicator for overall survival. Antibodies against CAIX serve as excellent excellent biomarkers of hypoxic regions in many solid tumors.
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